Mitropanos was born on April 2nd 1948 in the city of Trikala in northwest Thessaly where he lived until the age of 16. He began his musical career in 1964.
During his career worked with some of the best known Greek composers, such as Mikis Theodorakis, Stavros Xarhakos, Manos Hadjidakis, Giorgos Zampetas, Dimos Moutsis, Apostolos Kaldaras, Takis Mousafiris, Christos Nikolopoulos, Marios Tokas and Thanos Mikroutsikos and had been one of the top performers of Greek popular music for over four decades.
In the latest years, Mitropanos worked with a many younger singers and performed live all over Greece.
Two years ago, he made a North American Tour, playing to a near-capacity crowd at the Radio City Music Hall in New York in July of 2010.